I just posted my review of Totally Gross! The Game of Science at Games for Homeschooling.
The boys and I certainly laugh a lot and learn quite a bit of trivia playing this game. It does have a good measure of the gross and impolite.
The game ends with a little hands-on experiment, I feature I really like. Today, ds#1 had to weigh himself and figure out how much he would weigh on the moon (the card tells you that it would be 1/6th of your weight on Earth.)
As you will see on my gaming blog, I gripe a bit about the cheap components of educational games. I buy many other board games in the $20 price range with far more durable and aesthetically nicer parts, and they are more interesting games to play. Unfortunately, we pay for the educational value alone, which, in some cases, can be achieved with a home made game for far less money. I can't imagine writing up all those trivia questions, though.